How tramadol gives you relief from severe joint pain?

For treating moderate to severe pain, doctors around the globe prescribe people Tramadol, an opiate, and the narcotic-like drug, which can be easily procured from internet pharmacies like buytramadolonlinepills.com at a discounted price with just few clicks. This analgesic changes the pain sensations and feelings in the brain. It is one of most prescribed joint pain medications.

How Tramadol (Ultram) works for joint pain?

Tramadol (Ultram) is prescribed by the doctors to help a patient get relief from severe joint pain. Patients can easily purchase Tramadol 50mg using online pharmacies. This has now become the trend of this generation since people can get hold of Tramadol drug by just sitting in front of their system without the need to step out of their home. However, unlike the many other analgesics that directly work in the area of the pain, Tramadol works on the central nervous system and controls how the pain is felt in the body. How the neurotransmitters carry the pain sensations to the brain is what Tramadol has a control on. It acts in two ways –

  • This drug receives about 20% of its pain relieving effects from the sedative contents. This opioid content sedates the pains sensations and blocks the feelings between the brain and the nerves.
  • The other 80% of the painkilling effect is obtained by inhibiting the reuptake of norepinephrine and serotonin. These two brain chemicals that are associated with the feeling of pain in the brain.

Mechanism of Tramadol:

The pain is felt when sensation, movement, and vibration make the nerves in the different body parts and joints overly stimulated. The brain registers this feeling as discomfort and thus, makes one feel the pain. Tramadol works by decreasing the signaling process between the nerves and the brain and thus the body feels decreased pain. Ultram also helps by increasing the levels of certain chemicals such as epinephrine and serotonin that help in bringing a sense of well-being.

  1. Action on mu-opioid receptors:

Mu-opioid receptors are the neurotransmitters that actually receive and carry the pain sensations and feelings from the body joints. Tramadol works on these receptors and thus, decreases the transmission or pain carrying feeling.

  1. Inhibition of norepinephrine uptake:

O-desmethyltramadol is the active metabolic that actually inhibits the uptake of norepinephrine.

Why is tramadol a highly prescribed med for joint pain?

Unlike most other NSAIDs (Non-steroidal anti-inflammatory drugs), the opioid content of Ultram is very minimal. Hence, it is not highly addictive and is actually much safer. This drug comes in two forms – the immediate release Tramadol and the extended release Tramadol. Immediate release Tramadol (Ultram) has a half-life of 6 hours and hence, has to be taken after every 6 hours to wear off the pain feelings. If the joints pains are severe and chronic, the extended release form must be taken as it can have a lasting effect for 24 hours and hence, need to be taken only once daily.

Tramadol side effects:

Though considered to be safer than other painkillers and NSAIDs, this drug too can be habit forming and addictive, and hence it is always advisable to know how the medication will react in your body after consulting with the doctor before using it and make sure that you take it as prescribed by your doctor. Many are allergic to this drug and may experience common side effects such as nausea, dizziness, vomiting, constipation, drowsiness and headache. Immediate medical attention must be sought after so as to handle these side effects before the condition worsens or aggravates.